Dr. Abd-Elsayed’s research interests involve finding new clinical strategies to reduce chronic pain and for general pain management treatment. By carefully considering the pathology of the pain and treating the whole patient, we have been able to treat many patients with state-of-the-art therapies, including using advanced technology and modalities, that are successful in reducing or blocking pain and dramatically improving their quality of life.
Research in the Banks lab focuses on neural mechanisms of loss and recovery of consciousness under anesthesia, the overlap of these mechanisms with changes in arousal during natural sleep, the link between inflammation and brain function during postoperative delirium, and the mechanisms whereby psychedelics ameliorate psychiatric disorders (depression, substance use disorder).
Dr. Bevil’s lab investigates the incorporation of regional anesthesia techniques in the perioperative treatment of pain to improve patient outcomes as well as further evaluating patients’ understanding of pain and their postsurgical experience.
The Bilen-Rosas lab’s mission and passion is to find a solution to prevent catastrophic outcomes by developing a clinically useful respiratory monitoring device.
The Groose research group focuses on the role of the anesthesiologist in perioperative management to optimize outcomes in patients undergoing liver transplantation. Liver transplantation improves patient survival and reduces the burden of symptoms, but there is a significant risk of adverse events in the perioperative period. The anesthesiologist plays a pivotal role in determining which patients undergo liver transplantation and whether they are optimized, intraoperative management as well as immediate postoperative management in the ICU. Given the scarcity of liver allografts, improving recipient outcomes and graft survival is crucial.
Dr. Hartman’s current research focuses on quick implementation of therapy trial protocols to expeditiously bring novel treatments from the laboratory to the patient. Dr. Hartman concentrates on phase 2 and phase 3 clinical trials. University of Wisconsin-Madison is ideal for these types of trials because of the efficient Office of Clinical Trials staffed with highly skilled and motivated coordinators.
Research in the Hess Lab focuses on the relationship between platelet mitochondrial genetics and platelet function. Our goal is to understand how inherited and acquired platelet mitochondrial dysfunction may contribute to both bleeding and perioperative thrombotic events.
The Hogan Laboratory focuses on responses to anesthesia and surgery arising from genomic and epigenomic variation.
The Kay lab seeks to validate the immediate action of heparin and thereby the ability to safely go on cardiopulmonary bypass more rapidly than currently practiced even in patients with reduced ejection fraction.
Seeking novel treatments for chronic pain, the Lennertz research group aims to understand the transition from acute to chronic pain by studying inhibitory neurons in the brain. An additional interest is the analgesic potential of subtype-selective GABA modulators.
K.A. Kelly McQueen, MD, MPH, FASA
Dr. McQueen focuses on studying infrastructure and anesthesia and surgical outcomes in low and middle-income countries. Her 25+ years of research and programing has improved access to surgery and safe anesthesia, patient safety and patient outcomes in Subsaharan Africa and Central America.
The Pearce laboratory seeks to understand the neurophysiological basis of memory suppression under general anesthesia. Research focuses primarily on inhibitory neurons and synapses in the hippocampus, a brain region that is essential for the formation of new memories. Our current studies utilize genetic manipulations, brain slice electrophysiology, behavioral pharmacology, and large-scale optical imaging of cellular activity in freely exploring mice.
The Perouansky laboratory uses genetic tools available in the fruit fly (Drosophila melanogaster) to identify genetic determinants of anesthetic neurotoxicity.
Our research is focused on pediatric perioperative pain management strategies. By studying risks and complications as part of national and international databases, and through direct clinical research at our institution, our goal is to find innovative approaches and protocols that maximize non-opioid techniques and improve care for the youngest patients.