Perouansky Research Publications

"Stress Pathways Induced by Volatile Anesthetics and Failure of Preconditioning in a Mitochondrial Complex I Mutant."
Olufs ZPG, Wassarman DA, Perouansky M,  Anesthesiology  Vol 140  Iss 3  Pages 463-482  2024 Mar 1  PMID: 38118175  PMCID: PMC10932926

"A primordial target: Mitochondria mediate both primary and collateral anesthetic effects of volatile anesthetics."
Perouansky M, Johnson-Schlitz D, Sedensky MM, Morgan PG,  Experimental Biology And Medicine (Maywood, N.J.)  Vol 248  Iss 7  Pages 545-552  2023 Apr  PMID: 37208922  PMCID: PMC10350799

"Casting a Wider Net When Fishing for Mechanisms of Anesthesia."
Voss L, Sleigh JW, Perouansky M,  Anesthesiology  Vol 138  Iss 6  Pages 585-586  2023 Jun 1  PMID: 37158651

"The Serial Anesthesia Array for the High-Throughput Investigation of Volatile Agents Using Drosophila melanogaster."
Olufs ZPG, Johnson-Schlitz D, Wassarman DA, Perouansky M,  Journal Of Visualized Experiments : JoVE  Iss 192  2023 Feb 24  PMID: 36912551  PMCID: PMC10187765

"Mutations in Complex I of the Mitochondrial Electron-Transport Chain Sensitize the Fruit Fly (Drosophila melanogaster) to Ether and Non-Ether Volatile Anesthetics."
Borchardt LA, Scharenbrock AR, Olufs ZPG, Wassarman DA, Perouansky M,  International Journal Of Molecular Sciences  Vol 24  Iss 3  2023 Jan 17  PMID: 36768163  PMCID: PMC9915120

"Anesthetic Preconditioning of Traumatic Brain Injury Is Ineffective in a Drosophila Model of Obesity."
Johnson-Schlitz D, Fischer JA, Schiffman HJ, Scharenbrock AR, Olufs ZPG, Wassarman DA, et al. (incl. Perouansky M)  The Journal Of Pharmacology And Experimental Therapeutics  Vol 381  Iss 3  Pages 229-235  2022 Jun  PMID: 35347062  PMCID: PMC9190232

"Isoflurane Potentiation of GABA(A) Receptors Is Reduced but Not Eliminated by the β3(N265M) Mutation."
Lor C, Perouansky M, Pearce RA,  International Journal Of Molecular Sciences  Vol 21  Iss 24  2020 Dec 15  PMID: 33333797  PMCID: PMC7765171

"Interactions among Genetic Background, Anesthetic Agent, and Oxygen Concentration Shape Blunt Traumatic Brain Injury Outcomes in Drosophila melanogaster."
Scharenbrock AR, Schiffman HJ, Olufs ZPG, Wassarman DA, Perouansky M,  International Journal Of Molecular Sciences  Vol 21  Iss 18  2020 Sep 21  PMID: 32967238  PMCID: PMC7555144

"Ageing and genetic background influence anaesthetic effects in a D. melanogaster model of blunt trauma with brain injury(†)."
Schiffman HJ, Olufs ZPG, Lasarev MR, Wassarman DA, Perouansky M,  British Journal Of Anaesthesia  Vol 125  Iss 1  Pages 77-86  2020 Jul  PMID: 32466842  PMCID: PMC7418562