Source: Pubmed
"Delirium is associated with loss of feedback cortical connectivity."
Gjini K, Casey C, Kunkel D, Her M, Banks MI, Pearce RA, et al. (incl. Lennertz R) Alzheimer's & Dementia : The Journal Of The Alzheimer's Association 2023 Sep 11 [Preprint] PMID: 37695013
"Subanaesthetic doses of ketamine reduce but do not eliminate predictive coding responses: implications for mechanisms of sensory disconnection."
Wehrman JJ, Casey C, Tanabe S, Mohanta S, Filbey W, Weber L, et al. (incl. Pearce RA) British Journal Of Anaesthesia Vol 131 Iss 4 Pages 705-714 2023 Oct PMID: 37541951
"Resolution of elevated interleukin-6 after surgery is associated with return of normal cognitive function."
Taylor J, Wu JG, Kunkel D, Parker M, Rivera C, Casey C, et al. (incl. Lennertz R) British Journal Of Anaesthesia Vol 131 Iss 4 Pages 694-704 2023 Oct PMID: 37385855
"Control of contextual memory through interneuronal α5-GABA(A) receptors."
Zhu M, Abdulzahir A, Perkins MG, Chu CC, Krause BM, Casey C, et al. (incl. Pearce RA) PNAS Nexus Vol 2 Iss 4 Pages pgad065 2023 Apr PMID: 37056471 PMCID: PMC10089065
"Changes in Memory, Sedation, and Receptor Kinetics Imparted by the β2-N265M and β3-N265M GABA(A) Receptor Point Mutations."
Abdulzahir A, Klein S, Lor C, Perkins MG, Frelka A, Pearce RA, International Journal Of Molecular Sciences Vol 24 Iss 6 2023 Mar 15 PMID: 36982709 PMCID: PMC10053577
"Plasma HMGB1 levels in postoperative delirium."
Kunkel D, Parker M, Pearce RA, Sanders RD, Lennertz RC, British Journal Of Anaesthesia Vol 130 Iss 5 Pages e449-e451 2023 May PMID: 36858886 PMCID: PMC10273084
"Prospective analysis of plasma amyloid beta and postoperative delirium in the Interventions for Postoperative Delirium: Biomarker-3 study."
Payne T, Taylor J, Casey C, Kunkel D, Parker M, Blennow K, et al. (incl. Pearce RA) British Journal Of Anaesthesia Vol 130 Iss 5 Pages 546-556 2023 May PMID: 36842841 PMCID: PMC10273086
"Perioperative ischaemic brain injury and plasma neurofilament light: a secondary analysis of two prospective cohort studies."
Taylor J, Eisenmenger L, Lindroth H, Booth J, Mohanty R, Nair V, et al. (incl. Lennertz R) British Journal Of Anaesthesia Vol 130 Iss 2 Pages e361-e369 2023 Feb PMID: 36437124 PMCID: PMC9997085
"Greater tau pathology is associated with altered predictive coding."
Gjini K, Casey C, Tanabe S, Bo A, Parker M, White M, et al. (incl. Pearce RA) Brain Communications Vol 4 Iss 5 Pages fcac209 2022 PMID: 36226138 PMCID: PMC9547525
"Dynamic causal modelling of auditory surprise during disconnected consciousness: The role of feedback connectivity."
Casey CP, Tanabe S, Farahbakhsh Z, Parker M, Bo A, White M, et al. (incl. Pearce RA) NeuroImage Vol 263 Pages 119657 2022 Nov PMID: 36209793 PMCID: PMC10076444
"Sevoflurane dose and postoperative delirium: a prospective cohort analysis."
Taylor J, Payne T, Casey C, Kunkel D, Parker M, Rivera C, et al. (incl. Pearce RA) British Journal Of Anaesthesia Vol 130 Iss 2 Pages e289-e297 2023 Feb PMID: 36192219 PMCID: PMC9997074
"GABA facilitates spike propagation through branch points of sensory axons in the spinal cord."
Hari K, Lucas-Osma AM, Metz K, Lin S, Pardell N, Roszko DA, et al. (incl. Pearce RA) Nature Neuroscience Vol 25 Iss 10 Pages 1288-1299 2022 Oct PMID: 36163283 PMCID: PMC10042549
"Dose-dependent suppression of hippocampal contextual memory formation, place cells, and spatial engrams by the NMDAR antagonist (R)-CPP."
Zhu M, Perkins MG, Lennertz R, Abdulzahir A, Pearce RA, Neuropharmacology Vol 218 Pages 109215 2022 Nov 1 PMID: 35977628 PMCID: PMC9673467
"Delirium and Cortical Complexity: Divergent Changes in Alpha and Theta Bands."
Tanabe S, Parker M, Lennertz R, Pearce RA, Banks MI, Sanders RD, The Journals Of Gerontology. Series A, Biological Sciences And Medical Sciences Vol 77 Iss 11 Pages 2221-2222 2022 Nov 21 PMID: 35943896 PMCID: PMC9678193
"Impact of perioperative inflammation on days alive and at home after surgery."
Kunkel D, Parker M, Casey C, Krause B, Taylor J, Pearce RA, et al. (incl. Lennertz R) BJA Open Vol 2 Pages 100006 2022 Jun PMID: 37588271 PMCID: PMC10430844
"Increased expression of SLC25A1/CIC causes an autistic-like phenotype with altered neuron morphology."
Rigby MJ, Orefice NS, Lawton AJ, Ma M, Shapiro SL, Yi SY, et al. (incl. Pearce RA) Brain : A Journal Of Neurology Vol 145 Iss 2 Pages 500-516 2022 Apr 18 PMID: 35203088 PMCID: PMC9014753
"Distinct EEG signatures differentiate unconsciousness and disconnection during anaesthesia and sleep."
Casey CP, Tanabe S, Farahbakhsh Z, Parker M, Bo A, White M, et al. (incl. Pearce RA) British Journal Of Anaesthesia Vol 128 Iss 6 Pages 1006-1018 2022 Jun PMID: 35148892 PMCID: PMC9428919
"SLC13A5/sodium-citrate co-transporter overexpression causes disrupted white matter integrity and an autistic-like phenotype."
Rigby MJ, Orefice NS, Lawton AJ, Ma M, Shapiro SL, Yi SY, et al. (incl. Pearce RA) Brain Communications Vol 4 Iss 1 Pages fcac002 2022 Feb PMID: 35146426 PMCID: PMC8823335
"Postoperative delirium and changes in the blood-brain barrier, neuroinflammation, and cerebrospinal fluid lactate: a prospective cohort study."
Taylor J, Parker M, Casey CP, Tanabe S, Kunkel D, Rivera C, et al. (incl. Pearce RA) British Journal Of Anaesthesia Vol 129 Iss 2 Pages 219-230 2022 Aug PMID: 35144802 PMCID: PMC9465948
"Role of interleukin-18 in postoperative delirium: an exploratory analysis."
Wu JG, Taylor J, Parker M, Kunkel D, Rivera C, Pearce RA, et al. (incl. Lennertz R) British Journal Of Anaesthesia Vol 128 Iss 3 Pages e229-e231 2022 Mar PMID: 35090723 PMCID: PMC8988177
More Info
Robert A. Pearce, PhD
Professor
Department of Anesthesiology
University of Wisconsin
(608) 263-0208