Source: Pubmed
"The 3-Minute Diagnostic Confusion Assessment Method severity score correlates with the Delirium Rating Scale-Revised-98 and with biomarkers of delirium."
Rivera C, Kunkel D, Her M, Qureshi S, Pearce RA, Sanders RD, et al. (incl. Lennertz R) BJA Open Vol 14 Pages 100398 2025 Jun PMID: 40331035 PMCID: PMC12051057
"Reduced GABA(A, slow) synaptic inhibition in Alzheimer's disease."
MacIver MB, Pearce RA, Journal Of Alzheimer's Disease : JAD Vol 105 Iss 2 Pages 375-377 2025 May PMID: 40116686
"GFAP mutation and astrocyte dysfunction lead to a neurodegenerative profile with impaired synaptic plasticity and cognitive deficits in a rat model of Alexander disease."
Berman RF, Matson MR, Bachman AM, Lin NH, Coyne S, Frelka A, et al. (incl. Pearce RA) ENeuro Vol 12 Iss 3 2025 Mar 10 PMID: 40064497 PMCID: PMC11936449
"Divergent Effects of Ketamine and the Serotoninergic Psychedelic 2,5-Dimethoxy-4-Iodoamphetamine on Hippocampal Plasticity and Metaplasticity."
Zahid Z, Sultan ZW, Krause BM, Wenthur CJ, Pearce RA, Banks MI, Psychedelic Medicine (New Rochelle, N.Y.) Vol 2 Iss 3 Pages 166-177 2024 Sep PMID: 39669671 PMCID: PMC11633440
"The relationship of bispectral index values to conscious state: an analysis of two volunteer cohort studies."
Wehrman JJ, Schuller PJ, Casey CP, Scheinin A, Kallionpää RE, Valli K, et al. (incl. Pearce RA) British Journal Of Anaesthesia Vol 134 Iss 3 Pages 727-735 2025 Mar PMID: 39665912 PMCID: PMC11867084
"Association of preoperative to postoperative change in cerebrospinal fluid fibrinogen with postoperative delirium."
Payne T, Taylor J, Kunkel D, Konieczka K, Ingram F, Blennow K, et al. (incl. Pearce RA) BJA Open Vol 12 Pages 100349 2024 Dec PMID: 39429436 PMCID: PMC11490679
"Evaluation of putative signatures of consciousness using specific definitions of responsiveness, connectedness, and consciousness."
Casey CP, Tanabe S, Farahbakhsh ZZ, Parker M, Bo A, White M, et al. (incl. Pearce RA) British Journal Of Anaesthesia Vol 132 Iss 2 Pages 300-311 2024 Feb PMID: 37914581 PMCID: PMC10808836
"Delirium is associated with loss of feedback cortical connectivity."
Gjini K, Casey C, Kunkel D, Her M, Banks MI, Pearce RA, et al. (incl. Lennertz R) Alzheimer's & Dementia : The Journal Of The Alzheimer's Association Vol 20 Iss 1 Pages 511-524 2024 Jan PMID: 37695013 PMCID: PMC10840828
"Subanaesthetic doses of ketamine reduce but do not eliminate predictive coding responses: implications for mechanisms of sensory disconnection."
Wehrman JJ, Casey C, Tanabe S, Mohanta S, Filbey W, Weber L, et al. (incl. Pearce RA) British Journal Of Anaesthesia Vol 131 Iss 4 Pages 705-714 2023 Oct PMID: 37541951 PMCID: PMC10624770
"Resolution of elevated interleukin-6 after surgery is associated with return of normal cognitive function."
Taylor J, Wu JG, Kunkel D, Parker M, Rivera C, Casey C, et al. (incl. Lennertz R) British Journal Of Anaesthesia Vol 131 Iss 4 Pages 694-704 2023 Oct PMID: 37385855 PMCID: PMC10925892
"Control of contextual memory through interneuronal α5-GABA(A) receptors."
Zhu M, Abdulzahir A, Perkins MG, Chu CC, Krause BM, Casey C, et al. (incl. Pearce RA) PNAS Nexus Vol 2 Iss 4 Pages pgad065 2023 Apr PMID: 37056471 PMCID: PMC10089065
"Changes in Memory, Sedation, and Receptor Kinetics Imparted by the β2-N265M and β3-N265M GABA(A) Receptor Point Mutations."
Abdulzahir A, Klein S, Lor C, Perkins MG, Frelka A, Pearce RA, International Journal Of Molecular Sciences Vol 24 Iss 6 2023 Mar 15 PMID: 36982709 PMCID: PMC10053577
"Plasma HMGB1 levels in postoperative delirium."
Kunkel D, Parker M, Pearce RA, Sanders RD, Lennertz RC, British Journal Of Anaesthesia Vol 130 Iss 5 Pages e449-e451 2023 May PMID: 36858886 PMCID: PMC10273084
"Prospective analysis of plasma amyloid beta and postoperative delirium in the Interventions for Postoperative Delirium: Biomarker-3 study."
Payne T, Taylor J, Casey C, Kunkel D, Parker M, Blennow K, et al. (incl. Pearce RA) British Journal Of Anaesthesia Vol 130 Iss 5 Pages 546-556 2023 May PMID: 36842841 PMCID: PMC10273086
"Perioperative ischaemic brain injury and plasma neurofilament light: a secondary analysis of two prospective cohort studies."
Taylor J, Eisenmenger L, Lindroth H, Booth J, Mohanty R, Nair V, et al. (incl. Lennertz R) British Journal Of Anaesthesia Vol 130 Iss 2 Pages e361-e369 2023 Feb PMID: 36437124 PMCID: PMC9997085
"Greater tau pathology is associated with altered predictive coding."
Gjini K, Casey C, Tanabe S, Bo A, Parker M, White M, et al. (incl. Pearce RA) Brain Communications Vol 4 Iss 5 Pages fcac209 2022 PMID: 36226138 PMCID: PMC9547525
"Dynamic causal modelling of auditory surprise during disconnected consciousness: The role of feedback connectivity."
Casey CP, Tanabe S, Farahbakhsh Z, Parker M, Bo A, White M, et al. (incl. Pearce RA) NeuroImage Vol 263 Pages 119657 2022 Nov PMID: 36209793 PMCID: PMC10076444
"Sevoflurane dose and postoperative delirium: a prospective cohort analysis."
Taylor J, Payne T, Casey C, Kunkel D, Parker M, Rivera C, et al. (incl. Pearce RA) British Journal Of Anaesthesia Vol 130 Iss 2 Pages e289-e297 2023 Feb PMID: 36192219 PMCID: PMC9997074
"GABA facilitates spike propagation through branch points of sensory axons in the spinal cord."
Hari K, Lucas-Osma AM, Metz K, Lin S, Pardell N, Roszko DA, et al. (incl. Pearce RA) Nature Neuroscience Vol 25 Iss 10 Pages 1288-1299 2022 Oct PMID: 36163283 PMCID: PMC10042549
"Dose-dependent suppression of hippocampal contextual memory formation, place cells, and spatial engrams by the NMDAR antagonist (R)-CPP."
Zhu M, Perkins MG, Lennertz R, Abdulzahir A, Pearce RA, Neuropharmacology Vol 218 Pages 109215 2022 Nov 1 PMID: 35977628 PMCID: PMC9673467
More Info
Robert A. Pearce, PhD
Professor
Department of Anesthesiology
University of Wisconsin
(608) 263-0208