“Isoflurane Potentiation of GABAA Receptors Is Reduced but Not Eliminated by the β3(N265M) Mutation.”
Lor C, Perouansky M, Pearce RA, International Journal Of Molecular Sciences Vol 21 Iss 24 2020 Dec 15
“Association between plasma tau and postoperative delirium incidence and severity: a prospective observational study.”
Ballweg T, White M, Parker M, Casey C, Bo A, et al. (incl. Pearce RA), British Journal Of Anaesthesia Vol 126 Iss 2 458-466 2021 Feb
“Postoperative troponin increases after noncardiac surgery are associated with raised neurofilament light: a prospective observational cohort study.”
Sanders RD, Craigova L, Schessler B, Casey C, White M, et al. (incl. Pearce RA), British Journal Of Anaesthesia [Preprint] 2020 Nov 3
“Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways.”
Ruhl DA, Bomba-Warczak E, Watson ET, Bradberry MM, Peterson TA, et al. (incl. Pearce RA), Nature Communications Vol 10 Iss 1 3532 2019 Aug 6
“Wake Up, Neurons! Astrocytes Calling.”
Perouansky M, MacIver MB, Pearce RA, Anesthesiology Vol 130 Iss 3 361-363 2019 Mar
“Doc2-mediated superpriming supports synaptic augmentation.”
Xue R, Ruhl DA, Briguglio JS, Figueroa AG, Pearce RA, et al., Proceedings Of The National Academy Of Sciences Of The United States Of America Vol 115 Iss 24 E5605-E5613 2018 Jun 12
“Contrasting Effects of the γ-Aminobutyric Acid Type A Receptor β3 Subunit N265M Mutation on Loss of Righting Reflexes Induced by Etomidate and the Novel Anesthetic Barbiturate R-mTFD-MPAB.”
Amlong CA, Perkins MG, Houle TT, Miller KW, Pearce RA, Anesthesia And Analgesia Vol 123 Iss 5 1241-1246 2016 Nov
“Lipid-free Fluoropolymer-based Propofol Emulsions and Lipid Reversal of Propofol Anesthesia in Rats.”
Parks CL, Tucker W, Amlong CA, Mecozzi S, Pearce RA, Anesthesiology Vol 124 Iss 6 1328-37 2016 Jun
“Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABAA Receptors Reduces Memory Interference.”
Engin E, Zarnowska ED, Benke D, Tsvetkov E, Sigal M, et al. (incl. Pearce RA), The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience Vol 35 Iss 40 13698-712 2015 Oct 7
“Etomidate Impairs Long-Term Potentiation In Vitro by Targeting α5-Subunit Containing GABAA Receptors on Nonpyramidal Cells.”
Rodgers FC, Zarnowska ED, Laha KT, Engin E, Zeller A, et al. (incl. Pearce RA), The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience Vol 35 Iss 26 9707-16 2015 Jul 1
“Etomidate blocks LTP and impairs learning but does not enhance tonic inhibition in mice carrying the N265M point mutation in the beta3 subunit of the GABA(A) receptor.”
Zarnowska ED, Rodgers FC, Oh I, Rau V, Lor C, et al. (incl. Pearce RA), Neuropharmacology Vol 93 Pages 171-178 2015 Jun
“Measurement of NMDA Receptor Antagonist, CPP, in Mouse Plasma and Brain Tissue Following Systematic Administration Using Ion-Pair LCMS/MS.”
Gemperline E, Laha K, Scarlett CO, Pearce RA, Li L, Analytical Methods : Advancing Methods And Applications Vol 6 Iss 16 6389-6396 2014 Aug 21
“Spatiotemporal characteristics and pharmacological modulation of multiple gamma oscillations in the CA1 region of the hippocampus.”
Balakrishnan S, Pearce RA, Frontiers In Neural Circuits Vol 8 Pages 150 2014
“Enhancement of α5-containing γ-aminobutyric acid type A receptors by the nonimmobilizer 1,2-dichlorohexafluorocyclobutane (F6) is abolished by the β3(N265M) mutation.”
Burkat PM, Lor C, Perouansky M, Pearce RA, Anesthesia And Analgesia Vol 119 Iss 6 1277-84 2014 Dec
“A nonequilibrium binary elements-based kinetic model for benzodiazepine regulation of GABAA receptors.”
Goldschen-Ohm MP, Haroldson A, Jones MV, Pearce RA, The Journal Of General Physiology Vol 144 Iss 1 27-39 2014 Jul
“Midazolam and atropine alter theta oscillations in the hippocampal CA1 region by modulating both the somatic and distal dendritic dipoles.”
Balakrishnan S, Pearce RA, Hippocampus Vol 24 Iss 10 1212-31 2014 Oct
“Exceptionally stable fluorous emulsions for the intravenous delivery of volatile general anesthetics.”
Jee JP, Parlato MC, Perkins MG, Mecozzi S, Pearce RA, Anesthesiology Vol 116 Iss 3 580-5 2012 Mar
“Isoflurane enhances both fast and slow synaptic inhibition in the hippocampus at amnestic concentrations.”
Dai S, Perouansky M, Pearce RA, Anesthesiology Vol 116 Iss 4 816-23 2012 Apr
“Isoflurane impairs odour discrimination learning in rats: differential effects on short- and long-term memory.”
Pearce RA, Duscher P, Van Dyke K, Lee M, Andrei AC, et al., British Journal Of Anaesthesia Vol 108 Iss 4 630-7 2012 Apr
“How we recall (or don’t): the hippocampal memory machine and anesthetic amnesia.”
Perouansky M, Pearce RA, Canadian Journal Of Anaesthesia = Journal Canadien D’anesthesie Vol 58 Iss 2 157-66 2011 Feb
More Info
Robert A. Pearce, PhD
Professor
Department of Anesthesiology
University of Wisconsin
(608) 263-0208