Lennertz Research Publications

"Delirium is associated with loss of feedback cortical connectivity."
Gjini K, Casey C, Kunkel D, Her M, Banks MI, Pearce RA, et al. (incl. Lennertz R)  Alzheimer's & Dementia : The Journal Of The Alzheimer's Association  2023 Sep 11  [Preprint]  PMID: 37695013

"Resolution of elevated interleukin-6 after surgery is associated with return of normal cognitive function."
Taylor J, Wu JG, Kunkel D, Parker M, Rivera C, Casey C, et al. (incl. Lennertz R)  British Journal Of Anaesthesia  Vol 131  Iss 4  Pages 694-704  2023 Oct  PMID: 37385855

"Sevoflurane dose and postoperative delirium. Response to Br J Anaesth 2023; 130: e481-e482."
Taylor J, Payne T, Sanders RD, Lennertz RC,  British Journal Of Anaesthesia  Vol 131  Iss 1  Pages e17-e18  2023 Jul  PMID: 37088691

"Control of contextual memory through interneuronal α5-GABA(A) receptors."
Zhu M, Abdulzahir A, Perkins MG, Chu CC, Krause BM, Casey C, et al. (incl. Pearce RA)  PNAS Nexus  Vol 2  Iss 4  Pages pgad065  2023 Apr  PMID: 37056471  PMCID: PMC10089065

"The U-shaped curve predicting cognitive vulnerability to delirium severity."
Lennertz RC, Sanders RD,  Brain : A Journal Of Neurology  Vol 146  Iss 5  Pages 1743-1744  2023 May 2  PMID: 37019999

"Plasma HMGB1 levels in postoperative delirium."
Kunkel D, Parker M, Pearce RA, Sanders RD, Lennertz RC,  British Journal Of Anaesthesia  Vol 130  Iss 5  Pages e449-e451  2023 May  PMID: 36858886  PMCID: PMC10273084

"Prospective analysis of plasma amyloid beta and postoperative delirium in the Interventions for Postoperative Delirium: Biomarker-3 study."
Payne T, Taylor J, Casey C, Kunkel D, Parker M, Blennow K, et al. (incl. Pearce RA)  British Journal Of Anaesthesia  Vol 130  Iss 5  Pages 546-556  2023 May  PMID: 36842841  PMCID: PMC10273086

"Perioperative ischaemic brain injury and plasma neurofilament light: a secondary analysis of two prospective cohort studies."
Taylor J, Eisenmenger L, Lindroth H, Booth J, Mohanty R, Nair V, et al. (incl. Lennertz R)  British Journal Of Anaesthesia  Vol 130  Iss 2  Pages e361-e369  2023 Feb  PMID: 36437124  PMCID: PMC9997085

"Greater tau pathology is associated with altered predictive coding."
Gjini K, Casey C, Tanabe S, Bo A, Parker M, White M, et al. (incl. Pearce RA)  Brain Communications  Vol 4  Iss 5  Pages fcac209  2022  PMID: 36226138  PMCID: PMC9547525

"Sevoflurane dose and postoperative delirium: a prospective cohort analysis."
Taylor J, Payne T, Casey C, Kunkel D, Parker M, Rivera C, et al. (incl. Pearce RA)  British Journal Of Anaesthesia  Vol 130  Iss 2  Pages e289-e297  2023 Feb  PMID: 36192219  PMCID: PMC9997074

"Dose-dependent suppression of hippocampal contextual memory formation, place cells, and spatial engrams by the NMDAR antagonist (R)-CPP."
Zhu M, Perkins MG, Lennertz R, Abdulzahir A, Pearce RA,  Neuropharmacology  Vol 218  Pages 109215  2022 Nov 1  PMID: 35977628  PMCID: PMC9673467

"Delirium and Cortical Complexity: Divergent Changes in Alpha and Theta Bands."
Tanabe S, Parker M, Lennertz R, Pearce RA, Banks MI, Sanders RD,  The Journals Of Gerontology. Series A, Biological Sciences And Medical Sciences  Vol 77  Iss 11  Pages 2221-2222  2022 Nov 21  PMID: 35943896  PMCID: PMC9678193

"Connected consciousness after tracheal intubation in young adults: an international multicentre cohort study."
Lennertz R, Pryor KO, Raz A, Parker M, Bonhomme V, Schuller P, et al.  British Journal Of Anaesthesia  Vol 130  Iss 2  Pages e217-e224  2023 Feb  PMID: 35618535  PMCID: PMC10375493

"Impact of perioperative inflammation on days alive and at home after surgery."
Kunkel D, Parker M, Casey C, Krause B, Taylor J, Pearce RA, et al. (incl. Lennertz R)  BJA Open  Vol 2  Pages 100006  2022 Jun  PMID: 37588271  PMCID: PMC10430844

"Postoperative delirium and changes in the blood-brain barrier, neuroinflammation, and cerebrospinal fluid lactate: a prospective cohort study."
Taylor J, Parker M, Casey CP, Tanabe S, Kunkel D, Rivera C, et al. (incl. Pearce RA)  British Journal Of Anaesthesia  Vol 129  Iss 2  Pages 219-230  2022 Aug  PMID: 35144802  PMCID: PMC9465948

"Role of interleukin-18 in postoperative delirium: an exploratory analysis."
Wu JG, Taylor J, Parker M, Kunkel D, Rivera C, Pearce RA, et al. (incl. Lennertz R)  British Journal Of Anaesthesia  Vol 128  Iss 3  Pages e229-e231  2022 Mar  PMID: 35090723  PMCID: PMC8988177

"Amyloid deposition on positron emission tomography correlates with severity of perioperative delirium: a case-control pilot study."
Torres-Velázquez M, Parker M, Bo A, White M, Tanabe S, Pearce RA, et al. (incl. Lennertz R)  British Journal Of Anaesthesia  Vol 128  Iss 3  Pages e226-e228  2022 Mar  PMID: 34996589  PMCID: PMC8988176

"Reduced Electroencephalogram Complexity in Postoperative Delirium."
Tanabe S, Parker M, Lennertz R, Pearce RA, Banks MI, Sanders RD,  The Journals Of Gerontology. Series A, Biological Sciences And Medical Sciences  Vol 77  Iss 3  Pages 502-506  2022 Mar 3  PMID: 34958346  PMCID: PMC8893195

"CPP impairs contextual learning at concentrations below those that block pyramidal neuron NMDARs and LTP in the CA1 region of the hippocampus."
Laha K, Zhu M, Gemperline E, Rau V, Li L, Fanselow MS, et al. (incl. Pearce RA)  Neuropharmacology  Vol 202  Pages 108846  2022 Jan 1  PMID: 34687710  PMCID: PMC8627488

"Impact of postoperative delirium on days alive and at home after surgery: a prospective cohort study."
Kunkel D, Parker M, Casey C, Krause B, Pearce RA, Lennertz R, et al.  British Journal Of Anaesthesia  Vol 127  Iss 6  Pages e205-e207  2021 Dec  PMID: 34598782  PMCID: PMC8919668