Are you interested in one of our studies?
Contact Anesthesiology Research at research@anesthesia.wisc.edu and we will put you in contact with our research staff.
Dr. Alaa Abd-Elsayed
Product Surveillance Registry (PSR)
Site Investigator: Dr. Alaa Abd-Elsayed
The purpose of the Registry is to provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products. The Registry data is intended to benefit and support interests of patients, hospitals, clinicians, regulatory bodies, payers, and industry by streamlining the clinical surveillance process and facilitating leading edge performance assessment via the least burdensome approach.
Observational, Post Market Study in Treating Chronic Upper Extremity Limb Pain (Procura)
Site Investigator: Dr. Alaa Abd-Elsayed
This is a post-market, open-label, prospective, multi-center, observational study evaluating upper limb pain relief with the DTM™ SCS programming approach.
SCS Programming Study in Treating Intractable Chronic Back Pain (NOVA)
Site Investigator: Dr. Alaa Abd-Elsayed
This is an open-label prospective, randomized, controlled, multi-center study comparing DTM-SCS programming approach to Conventional SCS programming approach.
The purpose of this investigational study is to study the effects of Differential Target Multiplexed Spinal Cord Stimulation (DTM-SCS) in subjects with chronic, intractable pain of the trunk with or without lower limb pain, including unilateral or bilateral pain without prior history of spine surgery and refractory to conservative and surgical interventions.
Dr. Richard Lennertz
Regional Versus General Anesthesia for Promoting Independence After Hip Fracture (REGAIN)
Principal Investigator: Dr. Richard Lennertz
The purpose of this pragmatic multicenter prospective randomized trial of spinal versus general anesthesia for hip fracture surgery is to evaluate the association of anesthesia technique with functional recovery after hip fracture.
Dr. Patrick Meyer
Dr. Eric Simon
Pecto-Intercostal Fascial Plane Block for Enhanced Recovery After Cardiac Surgery
Principal Investigators: Dr. Patrick Meyer and Dr. Eric Simon
This prospective, double-blind, randomized controlled trial will evaluate whether bilateral pecto-intercostal fascial plane blocks (PIFB) with liposomal and standard bupivacaine reduce pain and opioid needs in patients undergoing cardiac surgery by median sternotomy compared to controls (sham blocks with saline). The primary hypothesis is that total daily opioid consumption in the 72 hours after surgery will be reduced by 25% for patients who receive effective regional anesthesia with liposomal bupivacaine via PIFB compared to patients who receive standard of care without effective regional anesthesia (saline only via PIFB).
Dr. Robert Pearce
Interventions for POstoperative Delirium-Biomarker-3 (IPOD-B3)
Principal Investigator: Dr. Robert Pearce
ClinicalTrials.gov Study Page
Based on prior models and prior cognitive theories, our Cognitive Disintegration model suggests a critical role of neural network connectivity in the predisposition to, and pathogenesis of, delirium. The neurophysiological hallmark of delirium is increased slow wave activity (SWA) on the electroencephalogram (EEG). We propose that delirium occurs as neural networks “disintegrate” through acute increases in SWA and investigating the underlying mechanisms may yield novel therapeutics for delirium. We are conducting a perioperative cohort study employing preoperative magnetic resonance imaging (MRI) and high-density EEG to probe changes in network connectivity and SWA and correlate these changes with changes in inflammation and cognition.
Interventions for POstoperative Delirium: Biomarker-PET 2 (IPOD-PET2)
Principal Investigator: Dr. Robert Pearce
This study focuses on the overlapping pathology of dementia and delirium. The inter-relationship between dementia and delirium is poorly understood with each condition predisposing to the other. This study (nested within IPOD-B3) will investigate associations with postoperative delirium (in the immediate postoperative period) and PET-amyloid levels detected.